Alcohol Research Group, Institute of Epidemiology and Behavioral Medicine, Medical Research Institute of San Francisco, 1816 Scenic Avenue, Berkeley, CA 94709
British Journal of Addiction 79:85-92, 1984 (with references updated).
While other psychoactive drugs have been a focus for attention and action in a variety of intergovernmental agencies, alcohol has been a continuing concern of only one global intergovernmental agency, the World Health organization. The present paper is an interpretation rather than an exact history of WHO's concern with alcohol. While the author has been at times an adviser to WHO's alcohol programme, this account is a personal and unofficial impression; a fuller account would undoubtedly benefit from reactions from many of the participants in the programme. Since it is based on the public record, the present interpretation gives more attention to published materials than to the unpublished meetings, training courses, and other activities which form much of the day-to-day substance of WHO's activities.
In contrast, "alcoholism" was on the agenda of the World Health Organization from its first assembly in 1948, and was a program focus during the years -- 1950 to 1955 -- that E.M. Jellinek served as a consultant in Geneva. This burst of activity left some enduring marks on the alcohol field. The "W.H.O. definition" of alcoholism (until recent years perhaps the most widely invoked definition in the field), Jellinek's chart of the "phases of alcohol addiction", and the full form of the Jellinek estimation formula, all made their first appearance in WHO publications of this period. Less noted than these concrete artifacts was the effect that Jellinek's WHO experience had in changing his conceptualizations of alcohol problems. The diversified conceptualization of "alcoholism" as a "genus" with many "species" presented in Jellinek's Disease Concept of Alcoholism(3) and other late works(4) reflected his recognition of the very different national traditions of conceptualization of and clinical experience with alcohol problems he had encountered in his WHO experience, and represented his attempt to accommodate them within a common nosological frame. Behind this reconceptualization lay a explicit recognition that the "Anglo-Saxon" focus on a narrow "alcoholism", as in his earlier chart of phases, tended to result in "the complete neglect of other important aspects of the problem"(5)
Though the publications resulting from developments in Jellinek's thought in his years at WHO certainly strained the limits of the developing orthodoxies about "alcoholism" (ironically oriented around his own earlier writings), more radical departures from the status quo had been edited out of the published versions. Anticipating the 1970s distinction between the broad field of "problems related to alcohol consumption", as defining the scope of public health concerns, and the narrower "alcohol dependence syndrome", as one "small part of the total of alcohol-related problems",(6) Jellinek had proposed in his original formulation in 1954 that "alcoholism" should be seen as only a small part of the public health interest in alcohol, and that the term "problems of alcohol" should therefore be adopted as the subject of discussions in an international public health framework.(7) Perhaps even more daringly, in his 1954 working paper Jellinek included an extended discussion of the "economic origin" of alcoholism -- a discussion which included an assertion of linkage between overall level of consumption and rates of alcoholism which would not appear again in publications under WHO auspices until the mid-1970s.
In any case, Jellinek's departure marked the end of sustained programme interest in the alcohol area at the Geneva headquarters of WHO for about 15 years. As it was diplomatically expressed in 1966, "the Organization was able to give very little consideration to problems of alcoholism for several years, partly because of the pressure of other topics to be dealt with in the mental health programme".(10)
The second extrabudgetary research effort under the auspices of WHO-EURO, known as the International Study of Alcohol Control Experiences, was organized as a collaborative enterprise of seven national research groups, each with their own national funding, with Klaus Mäkelä as the elected coordinator. While this study "found nothing that would require a revision" of the basic position of the earlier study, its emphasis was more social historical -- on understanding the interrelations of changes in the seven study sites in alcohol controls, consumption and consequences in the postwar era. The results of the study have been presented in three volumes,(21),(22),(23) two journal issues (Contemporary Drug Problems 10:1 & 2), and a variety of national reports. The study formed a major background to the recent WHO-EURO Symposium on Control of Alcohol Consumption (ref. 17).
In the meantime, the WHO programme in Geneva was built up in several different directions with the aid of extrabudgetary resources. This assistance began as an initiative of the U.S. National Institute on Alcohol Abuse and Alcoholism (NIAAA) in 1972. NIAAA support continued in various forms until 1981, and was followed by two years of support by the Nordic Council. Both for NIAAA and for the Nordic Council, a latent aim of the assistance was to build up a commitment on WHO's part to an ongoing alcohol programme; for NIAAA, the existence of such a programme at WHO enhanced the legitimacy of the field in its national political arena.(24) Given WHO's budget stringencies in recent years, however, the existence of extrabudgetary support, rather than evoking regular budgetary support, created the expectation that the programme would continue to draw support without regular budgetary allotments and positions. Besides Joy Moser's regular-budget position, which was extinguished on her retirement in 1981, the programme has had one senior staff position in the period of strong extrabudgetary support (from 1977 till June 1983), held by David Hawks, Irving Rootman, and Jan Ording on successive two-year appointments. As Pan and Bruun pointed out, these two WHO positions for alcohol, as of 1977 -- the only positions which were concerned with alcohol problems in any of the international agencies -- contrasted strongly with the total of 94 positions then existing for drug control in the international agencies.(25) At the moment of writing (October 1983), the programme is being supported with WHO budgetary funds on an interim basis, but without any regular programme staff positions.
In terms of the content of the Geneva programme, four main directions can be identified in the work of the last ten years. The initial support from NIAAA was for a study of "criteria for identifying and classifying disabilities related to alcohol consumption"; NIAAA was hoping to obtain a broadly-ranging nosology which would satisfy its domestic need for reimbursable but inclusive disease entities, in connection with its drive to gain health and social insurance coverage for alcoholism. The Steering Group for the WHO study saw it as inappropriate for WHO to hew so closely to one nation's agendas. Instead, drawing on materials prepared by Griffith Edwards and Milton Gross, the eventual report of a "Group of Investigators" distinguished between "alcohol-related disabilities" -- defined broadly but not in terms of disease -- and a much more narrowly-defined "alcohol dependence syndrome" -- distinguished in fact from the older term, "alcoholism", by its narrower and thus more exclusionary definition.(26) In the ensuing years, this solution -- with "disabilities" replaced by "alcohol-related problems" -- has provided a fairly stable rapprochement between psychiatric traditions of insistence on the importance and entitativity of addictive phenomena and the emergent epidemiological and social science traditions of "disaggregation" of alcohol-related problems (see, for instance, 6). Further developments on the two sides of the distinction have tended to proceed in separate arenas: the newly-christened "alcohol dependence syndrome" quickly made its way into general nosology by adoption as code 303 in the Ninth Revision of the International Classification of Diseases, and has been further developed conceptually in the context of the WHO Mental Health Division's general concern with the classification of psychiatric disorders.(27),(28) "Alcohol-related problems", on the other hand, became the conceptual arena within which WHO's other programme components -- on prevention strategies and national policies, and on the measurement and improvement of community responses, and on action at the international level -- developed.
The second line of work, on prevention strategies and national policies, had actually been initiated by the earlier compilation on national responses to alcohol and drug problems (ref.13). With contractual support from NIAAA, and through several successive drafts in the period 1976-1979, Joy Moser assembled, wrote and edited into shape a wide range of conceptual and programmatic materials from 80 countries on the prevention of alcohol-related problems (ref. 20).(29) This work provided a major input into the 1979 Expert Committee on Problems Related to Alcohol Consumption (ref. 6) and was further extended in the materials prepared for the Technical Discussions on "Alcohol Consumption and Alcohol-Related Problems: Development of National Policies and Programmes" held at the 1982 World Health Assembly.(30),(31)
The third line of work, and the most ambitious in terms of both resources and effort, has been the direction and coordination of collaborative studies on measuring and improving community and clinical responses to alcohol problems. The multifaceted WHO Study of Community Response to Alcohol-Related Problems, supported both by NIAAA and by the participating nations, and extending from 1976 to 1983, involved the collection and analysis of a variety of data from both rural and urban sites in Mexico, Scotland and Zambia, with associated studies in Canada and the U.S. In addition to assembling existing "background data", investigators in each participating country carried out a general population survey on drinking norms, behaviors and problems and on community responses to the problems, a qualitative study of community agency staff's perceptions and attitudes about alcohol problems, and a series of studies of alcohol-related problems as manifested in the caseloads both of alcohol-specific and of general community agencies. In a second phase, investigators attempted to intervene in and improve responses to alcohol problems both at community and national levels, while monitoring and reporting the success of the process. The study combined a number of conceptual and policy agendas: for instance, WHO's interest in practical work and training in developing countries, and in relating the response to alcohol problems to primary health care settings; an interest, deriving from work in Camberwell(32) and California,(33) in the social ecology of alcoholism treatment and its relation to informal community processes; a desire, related to the first line of work above, to test the cross-cultural applicability of the alcohol dependence syndrome.(34) Besides reports from each country, products of the study have included a variety of WHO documents, not yet in final published form(35),(36),(37),(38) and an ongoing collaborative cross-national analysis of the survey data. Some of the concerns of the Community Response Study, together with a clinical interest in operationizing the alcohol dependence syndrome and developing simple treatments appropriate for use in developing countries, have been carried further in a new 6-country collaborative study of early detection, diagnosis and treatment of alcohol problems.
The fourth line of work, on factors and collaboration at the international level, has primarily been developed since 1981. While there have been smaller efforts in this area, such an ongoing collaboration with the International Labour Organization and the International Council on Alcohol and Addictions on a review of existing national programmes for the handling of alcohol problems in the workplace, the major effort in this area has been the study of Public Health Aspects of Alcohol Availability. Part of this project, a study on the global market for alcohol and of the market influence of multinational corporations, was conducted in collaboration with the United Nations Conference on Trade and Development (UNCTAD). While summary reports on the project have been published,(39),(40),(41) further WHO work on the project was halted by WHO senior staff in the wake of press coverage.(42)
With the switch from extrabudgetary to interim regular-budget funds, the Geneva alcohol programmes is presently being reorganized under the direction of Norman Sartorius, as Director of the Mental Health Division, to concentrate on four major areas: (a) advocacy of the public health interest in the prevention and management of alcohol-related problems; (b) development and adaptation of technologies for the identification, prevention and management of alcohol-related problems found in the individual, the family and the community; (c) cooperation with countries int he development and implementation of national alcohol policies; and (d) international coordination and action.
The World Health Organization's activities with respect to alcohol can be seen as operating in three dimensions: in terms of symbolic activities, in terms of programmatic and coordinating activities, and in terms of the institutionalization of the program.
By symbolic activities is meant the panoply of arenas and channels available within WHO for emphasizing the importance of public health concerns about a topic. These activities often also carry a substantive meaning and implications, but an important thread connecting these activities is their potential value in increasing the salience of a topic on the policy and program agenda of a variety of audiences -- the WHO itself, its member governments, other international organizations, and the world community.
On the symbolic dimension, there has been substantial and cumulative activity in WHO in the last 10 years. Alcohol issues and programming have been the subject of two resolutions in the Executive Board and three resolutions in the World Health Assembly, of an Expert Committee, and of the "Technical Discussions" held during the 1982 World Health Assembly. Taken together, these resolutions and findings provide a broad legitimation for action by WHO's staff on alcohol problems, and embody much of the symbolic weight WHO can bring to bear on a topic.
There has also been a substantial record of activity, as detailed above, on information collation, definitional and conceptual development, and collaborative research. While not all the voluminous material which has been produced would find acceptance in a refereed journal, almost all of it has been useful and apropos. With more resources, more could be done. For instance, the information exchange on prevention that operated informally during Joy Moser's prevention project might well be institutionalized as an international clearinghouse activity. The World Health Assembly's mandate to improve data on alcohol-related problem statistics will require substantial resources if such statistics are to be gathered in developing countries. Such coordinating tasks as bringing public health considerations to bear in trade discussions have yet to be faced.
It is in terms of the third dimension, the institutionalization of the programme, that the picture appears most problematic, particularly in Geneva. As noted, a staff position has now been earmarked for alcohol in WHO-EURO, and there is a combined alcohol and drugs position in the Pan American Health Organization. Little alcohol activity is visible in the other regional offices. In Geneva, as mentioned, there is presently no permanent staff position on the alcohol programme. Joy Moser's long experience and wide range of contacts gave a continuity to the programme which can only be recaptured by stabilizing and institutionalizing the programme's staffing and activities.
But there is also another, more specific meaning of "control" -- the use of regulatory measures affecting the marketplace, in what is sometimes termed "health protection" activities. Such controls are a traditional instrument in the armamentarium of public health, and "alcohol control" in this special sense -- meaning state regulation of the production, distribution and promotion of alcohol -- also has a long history in the alcohol field. In the alcohol field, the idea of alcohol control emerged in the latter part of the 19th century as an alternative to the temperance movement's advocacy of prohibition.(43) The idea of eliminating or at least controlling the agent of harm -- alcohol -- fitted well with general public health models, and leading public health figures were prominent in temperance movements and alcohol control reforms in many countries in the late 19th and early 20th centuries.
For a variety of reasons -- including a reaction against Prohibition in North America -- restrictions on the availability of alcohol fell out of favor with political progressives, except perhaps in Scandinavia, by the 1930s. For public health professionals, mostly recruited from the ranks of political progressives, alcohol control thus became an embarrassing subject, to be avoided. There was no way to invoke the public health paradigm of environment-host-agent without raising the politically unacceptable issue of restrictions on the alcohol as the agent of harm.(44) Added to this problem, of course, is the fact that there are strong vested interests in the production and distribution of alcohol, and that these interests often have considerable influence at every level of government. To advocate the public health interest in alcohol controls, therefore, is necessarily a political act.
At the general level of government, as Jellinek suggested, it is perhaps the interplay of vested interests and popular sentiments which best explains the reluctance of governments, in the absence of an alcohol-oriented social movement or a national emergency, to tighten alcohol controls. But in the specific field of public health, the addition of the combination of paradigmatic attraction and political aversion may provide an explanation for the moth-and-flame approach of many public health institutions to alcohol controls. It is not only the World Health Organization which has commissioned and then shelved policy studies in this area; versions of this scenario have been played out in the last few years in Britain, Poland, the United States, Papua New Guinea, and Mexico, to my knowledge.
The issue has come up so frequently in the last few years because of the substantial revolution which has occurred in research thought on alcohol controls and their effectiveness (ref. 45). Studies and reports sponsored by WHO have played an important part in this change in consciousness among alcohol researchers. There is now no doubt that alcohol controls can reduce not only consumption but also alcohol-related problems, and that, contrary to common belief, they often most strongly affect the behavior of the heaviest drinkers (ref. 45). This does not mean that any alcohol control measure at any time will be effective; minimum conditions for the effectiveness of such measures are that they enjoy popular support, form a coherent programme. Nor does it necessarily mean that such measures should be invoked: that is a question for debate in the political process. But the new knowledge does mean that the political questions are there for debate -- the preemptive argument of ineffectiveness is no longer available. And the record so far suggests that attempts to sweep the new knowledge back under the rug -- to shelve the reports containing it -- is, for those motivated by a desire for a quiet life, often self-defeating.
ACKNOWLEDGEMENTS: Preparation of this paper was supported by a National Alcohol Research Center grant (AA 05595) from the U.S. National Institute on Alcohol Abuse and Alcoholism to the Alcohol Research Group, Institute of Epidemiology and Behavioral Medicine, Medical Research Institute of San Francisco.
1. Pan, L. (1975). Alcohol in Colonial Africa. Finnish Foundation for Alcohol Studies, Helsinki, vol. 22.
2. Bruun, K., Pan, L. and Rexed, I. (1975). The Gentlemen's Club: International Control of Drugs and Alcohol. University of Chicago Press, Chicago & London.
3. Jellinek, E.M. (1960). The Disease Concept of Alcoholism. Hillhouse Press, New Haven.
4. Jellinek, E.M. (1960). Alcoholism, a genus and some of its species. Canadian Medical Association J. 83, 1341-1345.
5. Jellinek, E.M. (1957). The world and its bottle. World Health 10 (4), 4-6. Abridged as: Cultural differences in the meaning of alcoholism, in D.J. Pittman and C.R. Snyder, eds, Society, Culture, and Drinking Patterns, 382-388. Wiley, New York, 1962.
6. WHO Expert Committee on Problems Related to Alcohol Consumption (1980). Problems Related to Alcohol Consumption. WHO Technical Report Series, No. 650.
7. Jellinek, E.M. (1954). International experience with the problem of alcoholism. WHO/MENT/58 & WHO/APD/ALC/12, 2 June. Prepared for the "Joint Meeting of Expert Committee on Mental Health and on Alcohol", Geneva, 27 September - 2 October 1954.
8. Jellinek's formulation could have been clearer. I believe this must be read as contrasting the "proportion of alcoholics" among heavy drinkers with the "absolute number" of alcoholics as a proportion of the total population; i.e., he is asserting that as consumption rises, although the proportion of alcoholics among heavy drinkers may fall, the rate of alcoholics in the overall population rises. Compare the 1975 report of a collaborative project under the auspices of the WHO Regional Office for Europe: "there is a tendency for the dispersion [of the distribution of alcohol consumption] to be somewhat higher in populations with low per capita consumption than in populations with high per capita consumption. . . . When the total consumption of alcohol in a country increases, the prevalence of heavy users in that country is likely to increase as well." [Pp. 32, 38 in: Bruun, K., Edwards, G., Lumio, M., Mäkelä, K., Pan, L., Popham, R.E., Room, R., Schmidt, W., Skog, O.-J., Sulkunen, P., and Österberg, E. (1975). Alcohol Control Policies in Public Health Perspective. Finnish Foundation for Alcohol Studies, Helsinki, vol. 25.]
9. Room, R. (1981). A farewell to alcoholism? A commentary on the WHO 1980 Expert Committee Report. Brit. J. Addiction 76, 115-123.
10. Moser, J. (1970). World Health Organization activities concerning alcoholism. In R.E. Popham, ed, Alcohol and Alcoholism, 385-388. University of Toronto Press, Toronto.
11. Grupo de estudios sobre la investigacion epidemiologica del alcoholismo en America Latina. (1966) Informe Final. Pan American Health Organization, Washington. Excerpted as "Notes towards an epidemiological study of alcoholism in Latin America", Drinking and Drug Practices Surveyor 6 (1972), 9-10.
12. WHO Expert Committee on Mental Health. (1967). Services for the Prevention and Treatment of Dependence on Alcohol and Other Drugs. World Health Organization, Geneva, Technical Report Series No. 363.
13. Moser, J. (1974). Problems and Programmes Related to Alcohol and Drug Dependence in 33 Countries. World Health Organization, Geneva, Offset Publication No. 6.
14. (Hawks, D., ed.) (1973). Epidemiology of Drug Dependence: Report on a Conference. World Health Organization Regional Office for Europe, Copenhagen, Publication EURO 5436 IV.
15. World Health Organization Regional Office for Europe. (1979). Public Health Aspects of Alcohol and Drug Dependence: Report on a WHO Conference. WHO-EURO, Copenhagen, EURO Reports and Studies No. 8.
16. Walsh, D. (1982). Alcohol-related Medicosocial Problems and Their Prevention. WHO-EURO, Copenhagen, Public Health in Europe Series No. 17.
17. Grant, M., ed. (1985). Alcohol Policies. WHO Regional Publications, European Series No. 18, Copenhagen.
18. World Health Organization Regional Office for Europe. (1973). Alcohol Control Policy and Public Health: Report on a Working Group. WHO-EURO, Copenhagen, Publication WHO-EURO 5455 IV. Reprinted in The Drinking and Drug Practices Surveyor 9 (1974), 1, 32-39.
19. Room, R. (1983). Former NIAAA Directors look back: Policymakers on the role of research. Drinking and Drug Practices Surveyor 19, 38-42.
20. Moser, J., compiler. (1980) Prevention of Alcohol Related Problems: An International Review of Preventive Measures, Policies and Programmes. Addiction Research Foundation, Toronto.
21. Mäkelä, K., Room, R., Single, E., Sulkunen, P., Walsh, B., with 13 others. (1981). Alcohol, Society, and the State: 1. A Comparative Study of Alcohol Control. Addiction Research Foundation, Toronto.
22. Single, E., Morgan, P. and de Lint, J., eds. (1981). Alcohol, Society, and the State: 2. The Social History of Control Policy in Seven Countries. Addiction Research Foundation, Toronto.
23. Giesbrecht, N., Cahannes, M., Moskalewicz, J., Österberg, E. and Room, R., eds. (1983). Consequences of Drinking: Trends in Alcohol Problem Statistics in Seven Countries. Addiction Research Foundation, Toronto.
24. Wiener, C. (1981). The Politics of Alcoholism: Building an Arena around a Social Problem. Transaction Books, New Brunswick, NJ.
25. Pan, L. and Bruun, K. (1979). Recent developments in international drug control. Brit. J. Addic. 74, 141-160.
26. Edwards, G., Gross, M.M., Keller, M., Moser, J. and Room, R., eds. (1977). Alcohol-Related Disabilities. World Health Organization, Geneva, Offset Publication No. 32.
27. Edwards, G., Arif, A. and Hodgson, R. (1981). Nomenclature and classification of drug- and alcohol-related problems: A WHO memorandum. Bulletin of the World Health Organization 59, 225-242.
28. WHO/ADAMHA Joint Project on Diagnosis and Classification of Mental Disorders and Alcohol- and Drug-Related Problems. (1981). "Alcohol- and drug-related problems", in Current State of Diagnosis and Classification in the Mental Health Field, 45-66. WHO Division of Mental Health, Geneva, WHO/MNH/81.11.
29. Moser, J., ed. (1980). Prevention of Alcohol-Related Problems: National and Sub-National Profiles of Alcohol use, Alcohol-Related Problems and Preventive Measures, Policies and Programmes. World Health Organization, Geneva, Document MNH/80.18.
30. Moser, J., ed. (1982). Alcohol Problems and National Policies: A Review Based on the Technical Discussions held during the Thirty-Fifth World Health Assembly, 1982. World Health Organization, Geneva, Document MNH/82.12.
31. Anonymous. (1982). Alcohol problems: a growing threat to health. WHO Chronicle 36, 222-225.
32. Edwards, G., Hawker, A., Hensman, C., Peto, J. and Williamson, V. (1973). Alcoholics known or unknown to agencies: Epidemiological studies in a London suburb. Brit. J. Psychiatry 123, 169-183.
33. Roizen, R. (1977). Barriers to alcoholism treatment. Social Research Group, Berkeley, Report F145.
34. Roizen, R. (1983). Alcohol dependence symptoms in cross-cultural perspective: A report of findings from the World Health Organization Study of Community Response to Alcohol-Related Problems. Presented at a Symposium on Cross-Cultural Studies of Drinking Problems, Farmington, Conn. May 5-7.
35. World Health Organization. (1981). Community Response to Alcohol Related Problems: Phase I Final Report, with 41 annexes. WHO, Geneva.
36. Rootman, I. (1982). WHO Project on Community Response to Alcohol-Related Problems: Phase II Report on Monitoring Responses to Alcohol Related Problems, with 4 annexes. WHO, Geneva. The substance of this and ref. 35 were published as: Rootman, I. and Moser, J. (1985). Community Response to Alcohol-Related Problems. NIAAA, Washington, DC.
37. Rootman, I. and Moser, J., eds. (1982). Guidelines for Investigating Alcohol Problems and Developing Appropriate Responses. WHO, Geneva.
38. Ritson, B. (1985). Community Response to Alcohol Problems: Review of an International Study. Public Health Paper No. 81. WHO, Geneva.
39. Anonymous. (1982). Public health aspects of international production, marketing and distribution of alcoholic beverages: Report of an 'informal consultation' held by the World Health Organization (WHO Geneva), 10-12 June 1981. Brit. J. Addic. 77, 349-356.
40. Cavanaugh, J. (1983). The trade debate. In Grant, M. and Ritson, B. Alcohol: The Prevention Debate, 120-126. Croom Helm, London.
41. Mintz, M. (1983). Alcohol, Inc: Bartenders to the world. Washington Post, Outlook section (4 September), C2.
42. Vichniac, I. (1983). Le commerce mondiale de l'alcool est de plus en plus domine par les societes transnationales affirme un rapport des Nations unies. Le Monde (15 February), 1, 42. [note added in 2000: The study was eventually published outside WHO auspices: Cavanagh, J. and Clairmonte, F.F. (1985) Alcoholic Beverages: Dimensions of Corporate Power. St. Martin's Press, New York. Meanwhile, in a compromised position, WHO put out two substitute publications on the topic: Walsh, B. and Grant, M. (1985) Public Health Implications of Alcohol Production and Trade. WHO Offset Publication No. 88. WHO, Geneva; Walsh, B. and Grant, M. (1985) Alcohol trade and its effects on public health, World Health Forum 6, 195-199.]
43. Room, R. (1984). Alcohol policies in industrial nations: Recent trends and alternative approaches. Journal of Primary Prevention, 4, 189-198.
44. Room, R. (1984). Alcohol control and public health. Annual Review of Public Health 5, 293-317.